WOMEN’S BODIES: THE EFFECTS OF SYPHILIS INFECTION
After the spirochaete gets into a break in skin or membranes and starts to multiply, it soon enters the lymph vessels and travels to the nearest lymph glands. From here it gets into the blood, where it continues to multiply and spreads throughout the body.
There are four stages of syphilis infection: primary, secondary, latent and tertiary. Symptoms of primary syphilis start between 9 and 90 days after infection. An ulcer, called a chancre, develops at the place where the infection got in. Typically this is a shallow ulcer with a raised edge and a firm base, and is usually painless and solitary, but there can be several chancres. It can be so small that you don’t notice it, or very large. The nearby lymph glands usually swell but aren’t tender.
The chancre is usually on or near the genitals but can be around the anus, mouth or anywhere that’s been in contact with a partner’s chancre. In women the chancre may be inside the vagina or on the cervix where it can’t be seen. During the primary stage of syphilis you don’t usually feel ill, so if the chancre isn’t noticed or can’t be seen you may not know you’ve been infected. The fluid that oozes from the ulcer is highly infectious.
If primary syphilis isn’t treated, the chancre heals within a few months and the infection proceeds to the secondary stage. The symptoms of secondary syphilis appear when the infection has been spread throughout the body by the blood, which takes between one and six months after the beginning of the primary stage. It begins like ‘flu with fever, sore throat, headache, loss of appetite, aching muscles and generally feeling unwell. The ulcer may reappear at its first site and others may break out in and around the genitals and mouth. Lymph glands throughout the body swell; you may notice them in the armpits, groin and neck. Wart-like lumps can develop on the genital and other skin, and your hair may start falling out. There is usually a rash that affects many lining membranes and the skin, including the palms and soles (most rashes don’t appear on these parts). Parts of the rash may break down to form very infectious ulcers.
This sounds terrible and it is: if secondary syphilis isn’t discovered and treated the symptoms can continue on and off for a year. This is the most infectious stage of the disease, and even after the symptoms have settled down you remain infectious for the following year during the next (latent) stage.
During the latent stage, which can last for the rest of your life, the infection is hidden because you have no symptoms.
However, if you’ve had no treatment the spirochaetes can be slowly causing inflammatory damage throughout the body that leads to the symptoms of tertiary syphilis.
Tertiary syphilis can affect almost any tissue or system in the body. The nervous system, heart and blood vessels, bones, skin, vision, hearing and many internal organs are at risk of severe damage from the chronic inflammation the spirochaete can cause. The symptoms depend on how much and which part is affected. They often mimic the symptoms of other diseases: tertiary syphilis used to be called ‘the great imitator’. More than two-thirds of people with latent syphilis don’t progress to tertiary syphilis.
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